Search Saint Charles hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Saint Charles
Family friendly
Spa pool
Check prices for these dates
Our top choices for Saint Charles hotels
9.4 out of 10, Exceptional, (1162)
"Room was nice, very clean."
Janet
Travelling with family
The price is AU$136
includes taxes & fees
19 Dec - 20 Dec
8.8 out of 10, Excellent, (1001)
"room was clean and comfortable"
Jennifer
Travelling solo
The price is AU$179
includes taxes & fees
25 Dec - 26 Dec
Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines AirportGreater South Side
8.6 out of 10, Excellent, (1685)
"Room was in an excellent condition, clean and equipped."
Emmanuel
Travelling for business
The price is AU$107
includes taxes & fees
25 Dec - 26 Dec
9.4 out of 10, Exceptional, (1000)
"Rooms are very clean & comfortable"
Eric
Travelling with small children
The price is AU$169
includes taxes & fees
15 Jan - 16 Jan 2026
Holiday Inn Express & Suites Des Moines Downtown by IHG
Holiday Inn Express & Suites Des Moines Downtown by IHGDowntown Des Moines
9.2 out of 10, Wonderful, (970)
"My room was clean and comfortable"
Monique
Travelling for business
The price is AU$151
includes taxes & fees
21 Dec - 22 Dec
9.2 out of 10, Wonderful, (1000)
"Very nice hotel, rooms are clean and modern."
Emily
Travelling with family
The price is AU$168
includes taxes & fees
25 Dec - 26 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Saint Charles attractions
Learn more about Saint Charles
Venture to sights like Imes Bridge as you discover the local area in Saint Charles.
Top Saint Charles Hotel Reviews
Recent Reviews in Saint Charles
Wildwood Lodge
10/10 Excellent
More cheap accommodation in Saint Charles
Secluded St Charles Cabin w/ Gas Grill + Fire Pit!
Saint Charles IA
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near 801 Grand
- Beaverdale Hotels
- Hotels near Blank Park Zoo
- Hotels near Buccaneer Arena
- B&B in Carlisle
- Caravan Parks in Carlisle
- Holiday Homes in Carlisle
- Luxury Hotels in Carlisle
- Carlisle Hotels
- Apartments in Clive
- Cheap Hotels in Clive
- Hotels with Parking in Clive
- Clive Hotels
- Business Hotels in Cumming
- Cumming Hotels
- Motels in Cumming
- De Soto Hotels
- Hostels in Des Moines
- Boutique Hotels in Des Moines
- Cheap Hotels in Des Moines
- Family Hotels in Des Moines
- Luxury Hotels in Des Moines
- Des Moines Hotels
- Hotels near Des Moines Intl.
- Lodges in Des Moines
- Motels in Des Moines
- Iowa Hotels
- Boutique Hotels in Downtown Des Moines
- Downtown Des Moines Hotels
- Historic East Village Hotels
- Indianola Hotels
- Hotels near Iowa Events Center
- Hotels near Iowa Hall of Pride
- Hotels near Iowa State Capitol Building
- Hotels near Jordan Creek Town Center
- Luxury Hotels in New Virginia
- New Virginia Hotels
- Cheap Hotels in Norwalk
- Norwalk Hotels
- Lgbt Welcoming Hotels in Osceola
- Osceola Hotels
- Hotels near Shady Oaks Golf Course
- Sherman Hill Hotels
- Truro Hotels
- Urbandale Hotels
- Luxury Hotels in Waukee
- Waukee Hotels
- Hotels near Wells Fargo Arena
- Cheap Hotels in West Des Moines
- Hotels with Parking in West Des Moines
- West Des Moines Hotels
- Pet Friendly Hotels in Windsor Heights
- Windsor Heights Hotels
- Motels in Windsor Heights
- Hotels with Parking in Winterset
- Winterset Hotels
- Motels in Winterset
- Flights to Iowa
- Flights to Carlisle
- Flights to Clive
- Flights to Des Moines Intl.
- Flights to Des Moines
- Flights to East Peru
- Flights to Murray
- Flights to New Virginia
- Flights to St. Marys
- Flights to Truro
- Flights to Windsor Heights
- Flights to Winterset
- Flights from Adelaide (ADL) to Des Moines (DSM)
- Flights from Brisbane (BNE) to Des Moines (DSM)
- Flights from Dallas (DFW) to Des Moines (DSM)
- Flights from Honolulu (HNL) to Des Moines (DSM)
- Flights from Houston (HOU) to Des Moines (DSM)
- Flights from New York (JFK) to Des Moines (DSM)
- Flights from Los Angeles (LAX) to Des Moines (DSM)
- Flights from Kansas City (MCI) to Des Moines (DSM)
- Flights from Melbourne (MEL) to Des Moines (DSM)
- Flights from New Orleans (MSY) to Des Moines (DSM)
- Flights from Chicago (ORD) to Des Moines (DSM)
- Flights from Port Lions (ORI) to Des Moines (DSM)
- Flights from Perth (PER) to Des Moines (DSM)
- Flights from San Francisco (SFO) to Des Moines (DSM)
- Flights from Singapore (SIN) to Des Moines (DSM)
- Flights from Salt Lake City (SLC) to Des Moines (DSM)
- Flights from Sydney (SYD) to Des Moines (DSM)
- Flights from Edmonton (YEG) to Des Moines (DSM)
- Flights from Vancouver (YVR) to Des Moines (DSM)
